While there was a time when Hugh Jackman was game to appear in the MCU as Wolverine, the timing never worked out, and as a result, that proverbial ship has sailed.
Of course, now that the MCU has access to the X-Men property, it’s expected that someday Wolverine will be rebooted with a different actor.
As such, the chances are also extremely slim we’ll ever get a proper pairing of Jackman’s Wolverine with Ryan Reynolds’ Deadpool, although with Deadpool 3 in development at Marvel Studios, perhaps Reynolds will finally be able to convince Jackman to don the claws one truly last time, even for just a cameo.