The actor recounted the phone call on Tuesday during a virtual conference hosted by CNN.
Dubbed Citizen by CNN, the event consisted in a series of discussions on issues pertaining to the upcoming presidential election.
She told Tapper she’s currently developing “a bunch of projects” as part of a deal with Apple TV+.
Louis-Dreyfus, who spoke at the Democratic National Convention in August, said she’s not supporting Biden because of the call, but for “a million other reasons”.