The 100th episode milestone means the show is eligible to live on in syndication in other networks.
The Batman prequel series Gotham has wrapped production on its final episode.
The show is wrapping up its five-season run starting early in 2019, concluding the tale of a young cop (and future Commissioner), James Gordon.
Tze Chun, who works as a producer/writer/director on the long-running series took to Twitter to announce the milestone, complete with a cake celebrating the 100-episode milestone.