Bucky may not pick up the actual Captain America shield in Infinity War or the MCU moving forward, but Stan hinted that Doctor Strange (Benedict Cumberbatch) could use his powers to try to make it more of a possibility.
Another possibility is that Doctor Strange transports Bucky to the world at the end of Captain America: Civil War, giving him an opportunity to pick up the shield that Rogers left behind.
Sebastian Stan teased Screen Rant with a hint of some Doctor Strange sorcery that he’s looking forward to in Avengers: Infinity War.
That Stan went in the direction of Doctor Strange’s powers when asked about his character and Captain America is intriguing to say the least.