The actor Michael Mando (Better Call Saul) has shared his first moment as an iconic Spider-Man villain with the online community.
Mando (who is also well known for his role in Orphan Black) plays an important character in Spider-Man: Homecoming even if non-comic fans might not realize it.
There does seem to be evidence that at least some form of The Sinister Six may appear in a Homecoming sequel.
In the comics, Gargan was created by the legendary partnership of Stan Lee and Steve Ditko, and first appeared in The Amazing Spider-Man in 1964.