That doesn’t solely make it impossible, mind you, but the story idea would probably have to be one-of-a-kind amazing in order to convince all involved to bring out the cameras anew.
The short answer is: probably not, given the fact that WandaVision is reportedly in the post-production phase, with the main chunk of filming completed.
But okay, so while it would be stellar for WandaVision to call on Spider-Man to add some aerial magic to the sitcom-aping narrative, is that something that could actually happen at this point in time?