Doctor Octopus stands a better chance of being brought back to the big screen, but judging by Spider-Man: Homecoming’s use of Vulture, Tinkerer and Shocker, there’s a good chance they’ll want to keep introducing villains who haven’t been used in live action yet rather than re-explore ones who’ve already had their time in the cinematic spotlight.
As for the actual chances of either of these antagonists being used in Spider-Man: Homecoming 2, Venom is unlikely to be considered.
Sony has a Venom movie in development that aiming for an R-rating and will not be connected to Tom Holland’s Spider-Man or any of the Marvel Cinematic Universe.
Fortunately, Spider-Man has one of the biggest rogues galleries in comic book history, and there are a lot of characters who still haven’t been pitted against the Webbed Wonder in movies, like Mysterio, Kraven the Hunter and The Scorpion.