Having taken on his first big U.S. TV acting role as Pablo Picasso in Genius in 2018, the actor appeared in a handful of movies in 2019, he showed up as a pirate king in 2020’s Doolittle, and he’s got several movies set for 2021, including the action sequel The Hitman’s Wife’s Bodyguard, the comedic drama Official Competition and the video game adaptation Uncharted with Tom Holland.
Banderas probably would have needed to be an actual vampire in order to make a cameo work for What We Do In the Shadows.
(Don’t expect for his rumored role in The New Mutants sequel, though, since that probably won’t happen.)