This means that the version of Spider-Man voiced by Shamiek Moore and the one played by Tom Holland might actually occupy neighboring universes.
It turns out there was initially a plan to suggest that, as Holland very nearly lent his voice to Into the Spider-Verse.
The animated movie is separate from the Marvel Cinematic Universe version of the character, though the premise of the film itself opens up the idea of multiverse, as Far From Home happens to be teasing as well.