The plot will revolve around Scamander losing track of numerous magical creatures in early 20th century America.
Eddie Redmayne will play the lead role of Newt Scamander in the film.
Whether or not the Patronus spell will be needed at any point in Fantastic Beasts and Where to Find _Them_ is something we don’t know yet.
While a Patronus doesn’t seem like something that would be particularly useful, the most recent trailers certainly show that the film has some very dark aspects to it and the darker the world the more the Patronus charm might be needed.
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