In particular, one would assume that Spider-Gwen would give way to a separate franchise, which could then lead to a Spider-Gwen v.
Not only will Miles Morales’s story be a viable franchise to revisit, should Spider-Man: Into The Spider-Verse take off, but any number of the other spider people could probably get their own adventures adapted as solo projects.
Plus, if Phil Lord and Chris Miller wanted to really swing their creative weight around in a truly impressive manner, they could try to set up a separate series of films following Nicholas Cage’s Spider-Man Noir adventures.
Gwenpool sort of situation, if the rights play out the right way.