Yes, speculation is already running rampant that Glover will be playing the Ultimate Universe version of Spider-Man, Miles Morales.
For those who may not know, Miles Morales took up the Spider-Man mantle in the Ultimate Marvel Universe (which takes place outside of the main Marvel Comics Universe) following the death of Peter Parker.
If that turns out to be true, that would mean that at some point, there will be more than one Spider-Man in the Marvel Cinematic Universe.
Rumors are circulating that the 2018 Sony animated Spider-Man movie will feature Morales, but that has yet to be confirmed.