So while Karen Gillan can neither confirm nor deny anything about The Avengers: Infinity War, it seems like a safe bet to assume that Nebula and Thanos will share a moment during the massive, cosmic event.
In Guardians of the Galaxy Vol. 2, Nebula opened up and explained her deep-seated hatred for Thanos — laying out how he slowly but surely removed her organic bodyparts and replaced them with machinery every time she would lose a fight to Gamora.
It’s not just about protecting the galaxy or preventing an Infinity Stone from falling into the wrong hands with her; she hates this guy, which is likely going to make for an incredibly dramatic scene in the end.